Developing advanced cancer models from diverse patient groups
University of California and UT Southwestern D-PDTC
This project creates special cancer models from diverse patients to help us learn more about advanced cancer and find better treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-11168885 on NIH RePORTER |
What this research studies
We are creating over 120 new patient-derived xenograft (PDX) models from individuals with advanced cancer, focusing on diverse racial and ethnic backgrounds. These models, which involve growing patient tumor cells in laboratory settings, help us understand how cancer develops and responds to different treatments. We will use these models to test existing FDA-approved drugs and new drug combinations to see which ones work best. This work aims to reduce health disparities in cancer care by ensuring our research reflects the diversity of patients affected by advanced cancer.
Who could benefit from this research
Good fit: Patients with advanced cancer, particularly those from racially and ethnically diverse backgrounds, could potentially contribute tumor samples to help create these research models.
Not a fit: Patients who do not have advanced cancer or are not able to provide tumor samples for model development would not directly benefit from this specific research opportunity.
Why it matters
Potential benefit: If successful, this work could lead to more effective, personalized treatments for advanced cancer, especially for diverse patient populations.
How similar studies have performed: Patient-derived xenograft models are a well-established tool in cancer research, and this project expands on existing successful infrastructure to include more diverse populations.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Carvajal Carmona, Luis Guillermo — University of California at Davis
- Study coordinator: Carvajal Carmona, Luis Guillermo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.