Developing a new therapy to treat heart failure without implants
Advancing Commercial Readiness of a No-implant Interatrial Shunt Therapy to Treat Heart Failure
This study is testing a new heart treatment that creates a small connection between two parts of the heart to help relieve symptoms for people with congestive heart failure, especially those who haven't found relief with other options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Alleviant Medical, INC. NIH-funded |
| Lab location | 1 site (Austin, UNITED STATES) |
| Project ID | NIH-10920111 on NIH RePORTER |
What this research studies
This research focuses on a novel approach to treating congestive heart failure (CHF) by using a no-implant interatrial shunt therapy. The therapy aims to create a connection between the left and right atrium of the heart, which could help lower elevated pressures in the left atrium, potentially alleviating symptoms of heart failure. The research will evaluate the safety and effectiveness of this therapy in patients with heart failure, particularly those with preserved or mid-range ejection fraction. By exploring this innovative treatment, the research seeks to provide new options for patients who currently have limited choices.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with heart failure, particularly those with preserved or mid-range ejection fraction.
Not a fit: Patients with heart failure who have reduced ejection fraction or those who do not meet the specific criteria for the interatrial shunt therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could offer a new, non-invasive treatment option for patients suffering from heart failure, improving their quality of life and reducing hospitalizations.
How similar studies have performed: Previous studies on interatrial shunting have shown promising safety and efficacy results, indicating potential for success in this novel approach.
Where this research is happening
Austin, UNITED STATES
- Alleviant Medical, INC. — Austin, United States (Active)
Researchers
- Principal investigator: Pate, Thomas Diffley — Alleviant Medical, INC.
- Study coordinator: Pate, Thomas Diffley
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.