Developing a new model for creating an HIV vaccine

Breaking the Barrier to an HIV Vaccine

['FUNDING_OTHER'] · UNIVERSITY OF COLORADO · NIH-10894882

This study is working on a new way to mimic HIV infection in animals to help scientists learn how the immune system fights the virus and find better vaccine options, which is really important after so many years of trying to develop an effective HIV vaccine.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF COLORADO (nih funded)
Locations1 site (Boulder, UNITED STATES)
Trial IDNIH-10894882 on ClinicalTrials.gov

What this research studies

This research focuses on creating a novel animal model that mimics key aspects of HIV infection, which will help in the development of an effective vaccine against HIV. By using this new model, researchers aim to study how the immune system responds to HIV and identify potential vaccine candidates. The approach involves understanding the immune correlates of protection and testing various vaccine strategies to find the most effective solutions. This work is crucial as it addresses the significant gap in HIV vaccine development, which has been a challenge for over 40 years.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at high risk for HIV infection or those living with HIV who are interested in new preventive measures.

Not a fit: Patients who are already receiving effective treatment for HIV and are not at risk for new infections may not benefit directly from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of an effective HIV vaccine, significantly reducing the incidence of HIV infections worldwide.

How similar studies have performed: While there have been various attempts to develop HIV vaccines, this approach using a new animal model is innovative and has not been extensively tested before.

Where this research is happening

Boulder, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus, HIV Infections

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.