NIH-funded research R01 grant

Developing a model to improve predictions from clinical data

Official title: Clinical foundation model for structured clinical data

Funded at University of Texas Hlth Sci Ctr Houston · NIH-11103340 · Data updated 2026-11-12

This study is working on a new way to use health data from different sources to make better predictions about medical events, which could help improve care and lower costs for patients like you.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Hlth Sci Ctr Houston
NIH-funded
Lab location1 site (Houston, United States)
Project startSeptember 1, 2023
Project endMay 31, 2027
Funding year2025
Award (this year)$351,000
NIH project number5R01LM014249-03
Project IDNIH-11103340 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients whose clinical data can be utilized for predictive modeling, particularly those with chronic conditions like COVID-19 or cardiac failure.

Less likely to help

Patients with very localized or unique clinical conditions that do not align with the broader predictive models may not benefit from this research.

What this research studies

This research focuses on creating a clinical foundation model (CFM) that utilizes structured clinical data from various sources, such as electronic health records (EHR) and claims data. By addressing the limitations of current predictive models, which often rely on localized data, the project aims to enhance the accuracy and generalizability of predictions for various clinical events. The approach includes developing a flexible framework for data integration, optimizing model architecture, and implementing innovative learning strategies. Patients' structured clinical data will be leveraged to improve healthcare efficiency and reduce costs.

Why it matters

Potential benefit: If successful, this research could lead to more accurate predictions of clinical outcomes, ultimately improving patient care and reducing healthcare costs.

How similar studies have gone: Other research has shown success in using large-scale clinical data to improve predictive modeling, indicating that this approach has potential for significant advancements.

Where this research is happening

  • University of Texas Hlth Sci Ctr Houston
    Houston, United States
    Active

Researchers

  • Principal investigator: Bekhet, Laila Rasmy Gindy — University of Texas Hlth Sci Ctr Houston
  • Study coordinator: Bekhet, Laila Rasmy Gindy

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.