Developing a long-acting treatment for HIV
IND-enabling studies for eCD4-Ig as a long-acting recombinant protein therapeutic
This study is working on a new treatment for HIV that uses a special protein to help your body fight the virus, and it aims to make it easy to take with just a shot every three months.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emmune, INC NIH-funded |
| Lab location | 1 site (Juno Beach, UNITED STATES) |
| Project ID | NIH-11183602 on NIH RePORTER |
What this research studies
This research focuses on creating a new therapeutic protein called eCD4-Ig, which targets HIV by mimicking parts of the virus's receptors. The goal is to enable a long-acting treatment that can be administered every three months through a simple injection. Before testing in humans, the research will conduct necessary laboratory studies to ensure safety and effectiveness. This includes assessing how the treatment interacts with human immune cells and conducting toxicity studies in animal models.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with HIV who are seeking new treatment options.
Not a fit: Patients who are not infected with HIV or those who are not eligible for new therapeutic interventions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a long-lasting and effective treatment option for individuals living with HIV.
How similar studies have performed: Previous research has shown promise in developing antibody-like therapeutics for HIV, indicating that this approach could be viable.
Where this research is happening
Juno Beach, UNITED STATES
- Emmune, INC — Juno Beach, United States (Active)
Researchers
- Principal investigator: Alpert, Michael David — Emmune, INC
- Study coordinator: Alpert, Michael David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.