Developing a gel to help regenerate tooth structure and fight infections

Multifunctional Colloidal Gel for Dentin Formation

NIH-funded research State University of New York at Buffalo · NIH-10620203

This study is testing a special gel that helps your teeth heal by encouraging the growth of new dentin and fighting off bacteria, so you can have better dental treatments that restore your teeth more effectively.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionState University of New York at Buffalo NIH-funded
Lab location1 site (Amherst, United States)
Project IDNIH-10620203 on NIH RePORTER

What this research studies

This research focuses on creating a multifunctional colloidal gel designed to enhance the regeneration of dentin, the tissue beneath the enamel of teeth, while also combating bacterial infections. The approach involves engineering a gel that can stimulate the remaining cells in the tooth to produce new dentin and provide an antibacterial effect. By using advanced biomaterials, the project aims to create a supportive environment that encourages healing and repair in damaged teeth. Patients may benefit from improved dental treatments that can restore tooth structure more effectively than current methods.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from dental caries or tooth decay who are seeking innovative treatment options.

Not a fit: Patients with healthy teeth or those not experiencing dental issues may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for dental decay and infections, potentially reducing the need for more invasive procedures.

How similar studies have performed: Other research in the field of biomaterials and dental regeneration has shown promise, indicating that this approach could be a meaningful advancement in dental treatments.

Where this research is happening

Amherst, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Bacterial Infectionsbacteria infectionbacterial disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.