Developing a comprehensive database for E. coli genetics and metabolism
Official title: Knowledgebase of Escherichia coli Genome and Metabolism
Funded at Sri International · NIH-10933447 · Data updated 2026-11-12
This study is working to improve a helpful online resource about E. coli, making it easier for scientists and educators to access the latest information on its genes and how it works, so they can use it in their research.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sri International NIH-funded |
| Lab location | 1 site (Menlo Park, United States) |
| Project start | September 30, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $1,455,257 |
| NIH project number | 5R24GM150703-02 |
| Project ID | NIH-10933447 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include scientists and researchers working on E. coli-related projects, particularly in fields like metabolic engineering and bioinformatics.
✕Less likely to help
Patients with conditions unrelated to E. coli or those not involved in scientific research may not receive direct benefits from this research.
What this research studies
This research focuses on enhancing the EcoCyc database, which provides detailed information about the genetics and metabolic pathways of Escherichia coli. The project aims to make this database freely accessible to scientists worldwide, allowing them to download data files and software applications for their research. By integrating new findings from biomedical literature and large-scale experiments, the EcoCyc database will serve as a vital resource for biologists, bioinformaticians, and educators interested in E. coli. The ongoing updates will ensure that users have access to the latest information on gene functions, metabolic pathways, and regulatory interactions.
Why it matters
Potential benefit: If successful, this research could significantly enhance our understanding of E. coli, leading to advancements in biotechnology and medicine.
How similar studies have gone: Previous research has successfully utilized similar bioinformatics approaches to enhance databases for other organisms, indicating a strong potential for success in this project.
Where this research is happening
-
Sri International
Menlo Park, United States Active
Researchers
- Principal investigator: Karp, Peter D — Sri International
- Study coordinator: Karp, Peter D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.