Detecting HPV-related throat cancer earlier in people with and without HIV
Earlier detection of HPV-related oropharynx cancer in people living with and without HIV
This study is looking to find better ways to detect HPV-related throat cancer early, especially for people living with HIV, by checking for certain markers in their saliva and blood, which could help improve screening methods in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11058695 on NIH RePORTER |
What this research studies
This research focuses on improving the early detection of HPV-related oropharynx cancer (HPV-OPC), particularly in individuals living with HIV, who are at a higher risk. The study will utilize a large cohort of participants to screen for specific oral and blood biomarkers associated with HPV-OPC. By comparing the progression of the disease in those with and without HIV, the research aims to enhance understanding of how HIV affects HPV persistence and cancer development. The findings could lead to better screening methods and inform future studies on the benefits and risks of such screenings.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals living with HIV and those without HIV who are at risk for HPV-related oropharynx cancer.
Not a fit: Patients who do not have HPV-related oropharynx cancer or are not at risk for HPV-related cancers may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection of HPV-related throat cancer, improving treatment outcomes for patients.
How similar studies have performed: Previous research has shown promise in using biomarkers for early detection of HPV-related cancers, indicating that this approach could be effective.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Fakhry, Carole — Johns Hopkins University
- Study coordinator: Fakhry, Carole
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.