Detecting hidden cancer cells in liver tumors
DNP-MRSI for the Detection of Latent, Treatment-Resistant Cellular Domains in HCC
This study is looking at new ways to find hidden cancer cells in liver cancer that don’t respond to regular treatments, so we can help doctors create better treatment plans for patients with this condition.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10436006 on NIH RePORTER |
What this research studies
This research focuses on improving the detection of latent, treatment-resistant cancer cells in hepatocellular carcinoma (HCC) using advanced imaging techniques. It aims to identify areas within tumors that may not respond to standard treatments, even when the overall tumor appears to shrink. By understanding how these cells adapt to their environment and remain viable, the research seeks to develop better imaging methods that can reveal these hidden cancer domains. This could lead to more effective treatment strategies for patients with HCC.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with hepatocellular carcinoma who may be undergoing treatment.
Not a fit: Patients with early-stage liver cancer or those who do not have hepatocellular carcinoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved detection of treatment-resistant cancer cells, allowing for more personalized and effective treatment options for patients with liver cancer.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques to detect hidden cancer cells, suggesting that this approach may be effective.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Gade, Terence P — University of Pennsylvania
- Study coordinator: Gade, Terence P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.