Detecting and understanding sepsis through advanced testing methods
Understand and Detect Sepsis: Pathogen Isolation, Biochemistry Assay, and Optofluidic Sensing
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA RIVERSIDE · NIH-10892113
This study is working on a faster and better way to find out if someone has sepsis by using a special chip that can quickly identify harmful bacteria in their blood, helping doctors give the right treatment sooner.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA RIVERSIDE (nih funded) |
| Locations | 1 site (RIVERSIDE, UNITED STATES) |
| Trial ID | NIH-10892113 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the diagnosis of sepsis, a severe condition often caused by bacterial infections. It aims to develop a rapid and effective method for isolating bacteria from blood samples and utilizing a CRISPR-based microfluidic chip to detect specific genetic markers of pathogens. The project also explores a novel optofluidic platform to enhance the detection process, making it faster and more accurate. By addressing current limitations in sepsis testing, this research seeks to provide timely interventions for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who are suspected of having sepsis or are at high risk for bacterial infections.
Not a fit: Patients with non-bacterial infections or those who do not present with symptoms of sepsis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the mortality rate associated with sepsis by enabling quicker and more accurate diagnoses.
How similar studies have performed: Previous research has shown promise in using CRISPR and microfluidic technologies for pathogen detection, indicating a potential for success in this novel approach.
Where this research is happening
RIVERSIDE, UNITED STATES
- UNIVERSITY OF CALIFORNIA RIVERSIDE — RIVERSIDE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DU, KE — UNIVERSITY OF CALIFORNIA RIVERSIDE
- Study coordinator: DU, KE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bacterial Infections