Detecting and targeting lung damage in severe respiratory conditions
Imaging and Targeting Lung Proteolysis in ARDS
['FUNDING_R01'] · YALE UNIVERSITY · NIH-10907654
This study is looking at a new way to spot early lung problems in people with acute respiratory distress syndrome (ARDS) so that doctors can improve treatments and help patients breathe better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YALE UNIVERSITY (nih funded) |
| Locations | 1 site (NEW HAVEN, UNITED STATES) |
| Trial ID | NIH-10907654 on ClinicalTrials.gov |
What this research studies
This research focuses on acute respiratory distress syndrome (ARDS), a serious condition characterized by severe lung injury. It aims to develop a new molecular imaging technique that can identify early signs of lung and vascular damage, which are often missed by current imaging methods. By understanding the activation of specific proteins involved in lung injury, the research seeks to improve treatment strategies and ventilation methods for patients with ARDS. This approach could lead to better management of the condition and potentially reduce complications such as heart failure.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with acute respiratory distress syndrome or those at high risk for developing this condition.
Not a fit: Patients with chronic respiratory conditions unrelated to ARDS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and more effective treatment options for patients suffering from ARDS.
How similar studies have performed: Previous research has shown promise in using molecular imaging techniques for similar conditions, indicating potential for success in this novel approach.
Where this research is happening
NEW HAVEN, UNITED STATES
- YALE UNIVERSITY — NEW HAVEN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SINUSAS, ALBERT J — YALE UNIVERSITY
- Study coordinator: SINUSAS, ALBERT J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acute Lung Injury, Acute Pulmonary Injury, Acute Respiratory Distress Syndrome, Adult Respiratory Distress Syndrome