Deep profiling of people at risk for frontotemporal dementia in India

Who could benefit from this research

What this research studies

Frontotemporal dementia often begins with changes in behavior, language, or movement, and can be influenced by inherited genes. The study will enroll presymptomatic relatives of FTLD patients in India to collect detailed clinical information, genetics, blood biomarkers, and advanced brain imaging. By tracing deep phenotypes and genotypic risk in about 300 high-risk individuals, researchers aim to map early disease signals and inform future preventive trials. The work will build on multimodal data to understand how the disease unfolds in a diverse population and prepare for future interventions. Participation could involve imaging, blood tests, and genetic analyses conducted with careful ethical oversight.

Why it matters

Where this research is happening

• National Institute of Mental Health and Neurosciences (Nimhans)
  Bangalore, India Active

Researchers

• Principal investigator: Arshad, Faheem — National Institute of Mental Health and Neurosciences (Nimhans)
• Study coordinator: Arshad, Faheem

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.