CureGN-Penn PCC: A patient-focused study on kidney diseases like FSGS, IgAN, MCD, and MN
Official title: CureGN-Penn PCC
Funded at University of Pennsylvania · NIH-11548464 · Data updated 2026-11-12
A large, long-term study from CureGN is following adults and children with common kidney diseases to understand how the diseases progress and how treatments affect them.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 16, 2013 |
| Project end | May 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $25,645 |
| NIH project number | 3U01DK100846-14S2 |
| Project ID | NIH-11548464 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adults or children diagnosed with MCD, FSGS, IgAN, or MN who are followed at CureGN participating sites and willing to provide data and biospecimens over time.
✕Less likely to help
Patients without these specific glomerular diseases or those not enrolled in CureGN sites may not directly benefit.
What this research studies
This project builds on CureGN's multi-site, observational approach to collect biospecimens, clinical data, and patient-reported outcomes from about 2,800 participants with MCD, FSGS, IgAN, or MN. It involves multiple clinical centers, a data coordinating center, and collaboration with patients and advocacy groups to create a rich resource for future research. Participants may contribute by sharing medical information, giving biospecimens, and completing surveys over time. Researchers will use these data to explore disease mechanisms and how therapies work in real-world settings.
Why it matters
Potential benefit: If successful, the study could lead to better personalized care and new insights into preventing kidney disease progression.
How similar studies have gone: Previous CureGN work has created a large, well-characterized cohort that supports ongoing translational research and has informed understanding of disease progression.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Holzman, Lawrence B. — University of Pennsylvania
- Study coordinator: Holzman, Lawrence B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.