CureGN-3: UNCPCC — following people with glomerular diseases to understand better treatments
Official title: CureGN-3: UNCPCC
Funded at Univ of North Carolina Chapel Hill · NIH-11545298 · Data updated 2026-11-12
A long-term, nationwide study follows adults and children with Berger's disease and related kidney diseases to learn about how they progress and respond to therapy.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | September 16, 2013 |
| Project end | May 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $41,850 |
| NIH project number | 3U01DK100867-14S1 |
| Project ID | NIH-11545298 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults and children diagnosed with Berger’s disease or related glomerular disorders who are receiving care at CureGN-affiliated centers and consent to long-term follow-up.
✕Less likely to help
Patients not enrolled in CureGN or who choose not to participate may not directly benefit from the study findings.
What this research studies
This project continues CureGN, a large observational study that collects clinical data, biospecimens, and patient-reported outcomes from people with diseases like FSGS, IgAN, MCD, and MN. Researchers use the gathered information to explore how these diseases develop and what factors influence outcomes, with a focus on potential paths to personalized care. Participants contribute through ongoing follow-up visits and by providing samples that can be used for future analyses. The effort is run by a network of major clinical centers and data coordinating teams to ensure high-quality, collaborative science.
Why it matters
Potential benefit: If successful, findings could lead to better disease monitoring, more tailored treatments, and improved quality of life for patients with glomerular diseases.
How similar studies have gone: Previous CureGN findings have advanced understanding of glomerular diseases and informed future research directions, though direct clinical benefits may take time to materialize.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Falk, Ronald J — Univ of North Carolina Chapel Hill
- Study coordinator: Falk, Ronald J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.