Creating tools to predict mental health issues in young people

Development and clinical validation of multimodal risk algorithms for predicting future internalizing psychopathology

['FUNDING_CAREER'] · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · NIH-10646253

This study is looking for ways to predict anxiety and depression in teens aged 12 to 20 by using brain scans and surveys, so we can find out what factors might help us support them better and get them the help they need early on.

Quick facts

Phase['FUNDING_CAREER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF VERMONT & ST AGRIC COLLEGE (nih funded)
Locations1 site (BURLINGTON, UNITED STATES)
Trial IDNIH-10646253 on ClinicalTrials.gov

What this research studies

This research focuses on developing and validating advanced algorithms that can predict the likelihood of internalizing mental health issues, such as anxiety and depression, in adolescents aged 12 to 20. By utilizing innovative neuroimaging techniques and machine learning methods, the study aims to analyze brain connectivity and psychosocial factors that contribute to these conditions. Participants may undergo assessments that include brain imaging and questionnaires to gather comprehensive data on their mental health and social environments. The goal is to identify key predictors that can help in early intervention and treatment strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who may be at risk for developing anxiety or depression.

Not a fit: Patients outside the age range of 12 to 20 or those without any risk factors for internalizing psychopathology may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved early detection and prevention strategies for mental health issues in adolescents.

How similar studies have performed: Other research has shown promise in using machine learning and neuroimaging to predict mental health outcomes, indicating that this approach has potential for success.

Where this research is happening

BURLINGTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Anxiety Disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.