Creating stem cell lines from Xenopus frogs
Official title: Establishment of xenopus stem cell lines
Funded at University of Wisconsin Milwaukee · NIH-10892196 · Data updated 2026-11-12
This study is working on creating special stem cell lines from a frog species called Xenopus laevis to help scientists better understand human diseases and how our bodies develop, making research more reliable than using human or mouse cells.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin Milwaukee NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $192,500 |
| NIH project number | 5R21OD033669-02 |
| Project ID | NIH-10892196 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with conditions that can be modeled using Xenopus, such as congenital heart disorders or neurodevelopmental disorders.
✕Less likely to help
Patients with conditions that cannot be effectively modeled using Xenopus or those who do not have a direct link to the biological processes being studied may not receive benefit from this research.
What this research studies
This research focuses on developing stem cell lines from the Xenopus laevis species, which is a valuable model for studying various biological processes and diseases. By establishing these cell lines, researchers aim to overcome limitations in current in vitro models that often rely on human or mouse cells, which can introduce variability. The project will utilize advanced techniques to isolate and culture these cells, enabling better analysis of cellular processes and disease modeling. This work could significantly enhance our understanding of human diseases and developmental biology.
Why it matters
Potential benefit: If successful, this research could provide new tools for studying human diseases and developing therapies using a more relevant biological model.
How similar studies have gone: Previous research has shown success in using Xenopus as a model organism for studying various diseases, indicating that this approach has potential for meaningful advancements.
Where this research is happening
-
University of Wisconsin Milwaukee
Milwaukee, United States Active
Researchers
- Principal investigator: Gouignard, Nadege — University of Wisconsin Milwaukee
- Study coordinator: Gouignard, Nadege
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.