Creating new tools for delivering genes using special nanoparticles
Development of peptoid-based barcodes for in vivo high-throughput screening of targeted nucleic acid delivery
This study is exploring new types of barcodes made from special molecules to help scientists track and improve how tiny particles deliver genetic material in the body, which could lead to better treatments for conditions that require gene therapy.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of North Texas Hlth Sci Ctr NIH-funded |
| Lab location | 1 site (Fort Worth, United States) |
| Project ID | NIH-11160703 on NIH RePORTER |
What this research studies
This research focuses on developing innovative barcodes made from peptoids to enhance the delivery of genetic material using nanoparticles. By utilizing unique DNA/RNA sequences, the project aims to improve the tracking and effectiveness of these nanoparticles in biological systems. The approach involves synthesizing a library of peptoid-based barcodes that can be easily identified and quantified, allowing for more efficient studies on how well these gene delivery systems work in living organisms. This could lead to better methods for gene therapy and other biomedical applications.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals with genetic conditions that could benefit from advanced gene therapy techniques.
Not a fit: Patients who do not have genetic disorders or conditions that require gene therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the efficiency and accuracy of gene delivery systems, potentially leading to better treatments for various genetic disorders.
How similar studies have performed: While the use of barcoding technology in gene delivery is an emerging field, similar approaches have shown promise in preliminary studies, indicating potential for success.
Where this research is happening
Fort Worth, United States
- University of North Texas Hlth Sci Ctr — Fort Worth, United States (Active)
Researchers
- Principal investigator: Kim, Jayoung — University of North Texas Hlth Sci Ctr
- Study coordinator: Kim, Jayoung
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.