NIH-funded research NIH-funded research

Creating new methods to make complex molecules with potential health benefits

Official title: Development of new methods and strategies for the synthesis of complex molecules

Funded at University of California-Irvine · NIH-11047685 · Data updated 2026-11-12

This study is exploring new and easier ways to create natural compounds that could help fight cancer and parasites, with the hope of finding better treatments for patients.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine
NIH-funded
Lab location1 site (Irvine, United States)
Project startMarch 5, 2024
Project endJanuary 31, 2029
Funding year2025
Award (this year)$336,303
NIH project number5R35GM153231-02
Project IDNIH-11047685 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients suffering from cancer or parasitic infections who may benefit from new therapeutic agents.

Less likely to help

Patients with conditions unrelated to cancer or parasitic infections may not receive any benefit from this research.

What this research studies

This research focuses on developing innovative ways to synthesize complex natural products that have promising biological activities, such as anti-cancer and anti-parasitic properties. By creating shorter and more efficient synthetic routes, the researchers aim to produce unnatural analogs of these compounds that could be beneficial in treating various diseases. The project involves advanced chemical techniques and strategies to streamline the assembly of these molecules, potentially leading to new therapeutic options for patients.

Why it matters

Potential benefit: If successful, this research could lead to the development of new medications that are more effective in treating cancer and parasitic infections.

How similar studies have gone: Previous research has shown success in developing new synthetic methods for natural products, indicating a promising potential for this approach.

Where this research is happening

  • University of California-Irvine
    Irvine, United States
    Active

Researchers

  • Principal investigator: Pronin, Sergey — University of California-Irvine
  • Study coordinator: Pronin, Sergey

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.