Creating new imaging tools to detect bacterial infections
Official title: Chemoenzymatic radiosyntheses of [18F]FDG-derived oligosaccharides for S. aureus detection
Funded at University of California, San Francisco · NIH-10982035 · Data updated 2026-11-12
This study is working on new ways to create special imaging tools that can help doctors quickly find bacterial infections, especially those caused by S. aureus, so they can diagnose and treat patients more effectively when they show symptoms.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | July 17, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $780,034 |
| NIH project number | 1R01AI181378-01A1 |
| Project ID | NIH-10982035 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients presenting with symptoms of bacterial infections, particularly those related to S. aureus.
✕Less likely to help
Patients with non-bacterial infections or those not exhibiting acute symptoms may not benefit from this research.
What this research studies
This research focuses on developing innovative methods to create specific PET radiotracers that can help detect bacterial infections, particularly those caused by S. aureus. By using a unique chemoenzymatic approach, the team aims to synthesize these tracers from a common oncologic tracer, making them readily available for use in acute care settings. The goal is to enhance the ability of clinicians to diagnose infections quickly and accurately when patients show symptoms. This work could lead to improved imaging techniques that are tailored for identifying specific bacteria in the body.
Why it matters
Potential benefit: If successful, this research could significantly improve the diagnosis and treatment of bacterial infections, leading to better patient outcomes.
How similar studies have gone: While the application of chemoenzymatic methods in PET imaging is relatively novel, preliminary data suggests promising results in similar approaches.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Wilson, David M — University of California, San Francisco
- Study coordinator: Wilson, David M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.