Creating new disinfectants to fight resistant bacteria

The Development of Novel Disinfectants to Overcome Bacterial Resistance

NIH-funded research Villanova University · NIH-10974662

This study is working on creating new disinfectants that are better at fighting tough bacterial infections, especially for patients who need stronger protection against germs that don't respond to regular treatments.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionVillanova University NIH-funded
Lab location1 site (Villanova, United States)
Project IDNIH-10974662 on NIH RePORTER

What this research studies

This research focuses on developing innovative disinfectants to combat bacterial infections that have become resistant to traditional treatments. The team aims to create new compounds that go beyond existing disinfectants, specifically exploring phosphorus-based alternatives to improve effectiveness and reduce toxicity. By studying how different chemical structures influence the ability to kill bacteria, the researchers hope to design disinfectants that can tackle even the most resistant strains. Patients may benefit from these advancements through improved infection control and reduced healthcare-associated infections.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at high risk for bacterial infections, such as patients undergoing surgery or those with compromised immune systems.

Not a fit: Patients who are not at risk for bacterial infections or those with non-bacterial conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective disinfectants that significantly reduce the incidence of bacterial infections in healthcare settings.

How similar studies have performed: Other research has shown promise in developing novel disinfectants, indicating that this approach could lead to significant advancements in infection control.

Where this research is happening

Villanova, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Bacterial Infections
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.