Creating models to understand how endometriomas form
Official title: Physiomimetic Models of Endometrioma Initiation
Funded at University of Illinois at Urbana-Champaign · NIH-11142198 · Data updated 2026-11-12
This study is looking at endometriosis, a condition that causes pain and can affect fertility, by creating a special model to better understand how endometriomas form and grow, with the hope of finding better treatments for those who have it.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Urbana-Champaign NIH-funded |
| Lab location | 1 site (Champaign, United States) |
| Project start | March 19, 2025 |
| Project end | December 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $643,049 |
| NIH project number | 1R01HD118600-01 |
| Project ID | NIH-11142198 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with endometriosis, particularly those experiencing endometriomas.
✕Less likely to help
Patients who do not have endometriosis or related conditions may not benefit from this research.
What this research studies
This research focuses on endometriosis, a condition affecting many menstruating individuals, which can lead to chronic pain and infertility. The team aims to develop a tissue engineering model that mimics the environment of endometriomas, allowing for a better understanding of how these lesions form and persist. By studying the processes involved in lesion initiation and growth, the research seeks to uncover the underlying mechanisms that contribute to this condition. This innovative approach could lead to improved treatment strategies for those affected by endometriosis.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for individuals suffering from endometriosis.
How similar studies have gone: While there has been some research on endometriosis, the specific approach of using tissue engineering models for endometrioma study is relatively novel.
Where this research is happening
-
University of Illinois at Urbana-Champaign
Champaign, United States Active
Researchers
- Principal investigator: Harley, Brendan a. — University of Illinois at Urbana-Champaign
- Study coordinator: Harley, Brendan a.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.