Creating models to understand how endometriomas form

Physiomimetic Models of Endometrioma Initiation

NIH-funded research University of Illinois at Urbana-Champaign · NIH-11142198

This study is looking at endometriosis, a condition that causes pain and can affect fertility, by creating a special model to better understand how endometriomas form and grow, with the hope of finding better treatments for those who have it.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Urbana-Champaign NIH-funded
Lab location1 site (Champaign, United States)
Project IDNIH-11142198 on NIH RePORTER

What this research studies

This research focuses on endometriosis, a condition affecting many menstruating individuals, which can lead to chronic pain and infertility. The team aims to develop a tissue engineering model that mimics the environment of endometriomas, allowing for a better understanding of how these lesions form and persist. By studying the processes involved in lesion initiation and growth, the research seeks to uncover the underlying mechanisms that contribute to this condition. This innovative approach could lead to improved treatment strategies for those affected by endometriosis.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with endometriosis, particularly those experiencing endometriomas.

Not a fit: Patients who do not have endometriosis or related conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment options for individuals suffering from endometriosis.

How similar studies have performed: While there has been some research on endometriosis, the specific approach of using tissue engineering models for endometrioma study is relatively novel.

Where this research is happening

Champaign, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.