Creating long DNA fragments efficiently for genetic research
Multiplexed In Vivo DNA Assembly
This study is working on a new way to create long pieces of DNA more easily and affordably, which could eventually help improve treatments for genetic conditions by making better genetic therapies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Bacstitch DNA INC. NIH-funded |
| Lab location | 1 site (Los Altos, UNITED STATES) |
| Project ID | NIH-10794331 on NIH RePORTER |
What this research studies
This research focuses on developing a new method for synthesizing long DNA fragments in a high-throughput and cost-effective manner. By utilizing advanced microarray printing technologies and enzymatic synthesis, the project aims to overcome current limitations in DNA assembly techniques. Patients may benefit indirectly as this research could lead to advancements in genetic therapies and synthetic biology applications that improve treatment options for various genetic conditions. The methodology involves assembling DNA elements in living cells, allowing for more accurate and efficient production of genetic materials.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with genetic disorders or those interested in cutting-edge genetic therapies.
Not a fit: Patients with conditions unrelated to genetic therapies or synthetic biology may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could significantly enhance the development of genetic therapies and synthetic biology applications, leading to improved treatment options for patients.
How similar studies have performed: Other research has shown promise in similar approaches to DNA synthesis and assembly, indicating potential for success in this novel method.
Where this research is happening
Los Altos, UNITED STATES
- Bacstitch DNA INC. — Los Altos, United States (Active)
Researchers
- Principal investigator: Levy, Sasha F — Bacstitch DNA INC.
- Study coordinator: Levy, Sasha F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.