Creating kidney organoids to study kidney injury
Official title: Patient-Derived Kidney Organoids For Modeling Kidney Injury
Funded at Stanford University · NIH-11042822 · Data updated 2026-11-12
This study is looking at tiny, lab-grown versions of kidneys to learn more about kidney injuries and how they can be treated, which could help people with kidney problems like acute kidney injury or transplant rejection.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | March 1, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $165,996 |
| NIH project number | 5K08DK132509-03 |
| Project ID | NIH-11042822 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults experiencing acute kidney injury or those at risk of kidney-related complications.
✕Less likely to help
Patients with chronic kidney disease who are not experiencing acute injury may not benefit directly from this research.
What this research studies
This research focuses on developing patient-derived kidney organoids to better understand kidney injuries, particularly acute kidney injury and allograft rejection. By using these organoids, researchers aim to replicate the complex interactions between different kidney cell types in a controlled environment. The study will investigate how kidney cells respond to injury and identify signals that could either protect or worsen kidney damage. This approach may lead to new therapies for kidney diseases by providing insights into their underlying mechanisms.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments for acute kidney injury and improve outcomes for patients with kidney diseases.
How similar studies have gone: Previous research using organoid models has shown promise in understanding various diseases, suggesting that this approach could yield valuable insights for kidney injury as well.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Sutha, Ken — Stanford University
- Study coordinator: Sutha, Ken
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.