Creating genetically modified Xiphophorus fish to study cancer and other diseases

Development of genome-modified Xiphophorus

NIH-funded research Texas State University · NIH-10689339

This study is looking at specially modified fish to help us learn more about cancer and other diseases, which could eventually lead to better treatments or ways to prevent conditions like skin cancer for patients.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionTexas State University NIH-funded
Lab location1 site (San Marcos, United States)
Project IDNIH-10689339 on NIH RePORTER

What this research studies

This research focuses on developing genetically modified Xiphophorus fish, which are valuable models for understanding cancer and other diseases. By utilizing advanced genomic techniques, the project aims to identify and validate genes that influence tumor progression and other health conditions. Patients may benefit from insights gained through this research, as it could lead to new treatments or preventive strategies for diseases like skin cancer. The study leverages the unique biological characteristics of Xiphophorus to explore complex disease mechanisms.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research include individuals at risk for skin cancer or those interested in advancements in cancer treatment.

Not a fit: Patients with conditions unrelated to cancer or those not at risk for skin-related diseases may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating various cancers and related health issues.

How similar studies have performed: Previous research using Xiphophorus as a model organism has shown promise in understanding cancer biology and other diseases, indicating a strong potential for success in this approach.

Where this research is happening

San Marcos, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancersneoplasm/cancerSkin Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.