Creating genetically modified Xiphophorus fish to study cancer and other diseases
Official title: Development of genome-modified Xiphophorus
Funded at Texas State University · NIH-10689339 · Data updated 2026-11-12
This study is looking at specially modified fish to help us learn more about cancer and other diseases, which could eventually lead to better treatments or ways to prevent conditions like skin cancer for patients.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas State University NIH-funded |
| Lab location | 1 site (San Marcos, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $188,125 |
| NIH project number | 5R21OD031910-02 |
| Project ID | NIH-10689339 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals at risk for skin cancer or those interested in advancements in cancer treatment.
✕Less likely to help
Patients with conditions unrelated to cancer or those not at risk for skin-related diseases may not receive direct benefits from this research.
What this research studies
This research focuses on developing genetically modified Xiphophorus fish, which are valuable models for understanding cancer and other diseases. By utilizing advanced genomic techniques, the project aims to identify and validate genes that influence tumor progression and other health conditions. Patients may benefit from insights gained through this research, as it could lead to new treatments or preventive strategies for diseases like skin cancer. The study leverages the unique biological characteristics of Xiphophorus to explore complex disease mechanisms.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating various cancers and related health issues.
How similar studies have gone: Previous research using Xiphophorus as a model organism has shown promise in understanding cancer biology and other diseases, indicating a strong potential for success in this approach.
Where this research is happening
-
Texas State University
San Marcos, United States Active
Researchers
- Principal investigator: Schartl, Manfred — Texas State University
- Study coordinator: Schartl, Manfred
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.