Creating gene editing tools for marmosets
Tools for gene editing in marmosets
['FUNDING_U01'] · JOHNS HOPKINS UNIVERSITY · NIH-10892191
This study is working on new ways to change the genes of marmosets, small monkeys that help us learn about brain function and diseases, so we can better understand human brain disorders and improve future research in this area.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10892191 on ClinicalTrials.gov |
What this research studies
This research focuses on developing advanced tools and techniques for genetically modifying marmosets, which are important models for studying brain function and diseases. The project involves refining genome editing technologies, improving breeding methods, and establishing protocols for embryo culture and genetic screening. By creating a large colony of marmosets and utilizing interdisciplinary expertise, the research aims to generate genetically modified marmosets that can help in understanding human brain disorders. This work will ultimately provide essential resources for future studies in neurobiology.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals interested in genetic studies related to brain health and disorders.
Not a fit: Patients with conditions unrelated to brain diseases or those not interested in genetic research may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for brain diseases in humans.
How similar studies have performed: Other research has shown success with similar gene editing approaches in animal models, indicating potential for this novel application.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, XIAOQIN — JOHNS HOPKINS UNIVERSITY
- Study coordinator: WANG, XIAOQIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Brain Diseases, Brain Disorders