Creating diverse cancer models to improve treatment options
PDX Core
['FUNDING_OTHER'] · VIRGINIA COMMONWEALTH UNIVERSITY · NIH-11161646
This study is working to create models using tumor samples from people of different racial and ethnic backgrounds with advanced cancer, so we can better understand how cancer behaves and responds to treatments, ultimately helping to improve care for everyone.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VIRGINIA COMMONWEALTH UNIVERSITY (nih funded) |
| Locations | 1 site (RICHMOND, UNITED STATES) |
| Trial ID | NIH-11161646 on ClinicalTrials.gov |
What this research studies
This research focuses on developing patient-derived xenograft (PDX) models that represent diverse racial and ethnic populations, particularly those with advanced cancer. By collecting and expanding viable tumor tissues from underrepresented groups, the project aims to enhance the understanding of cancer characteristics and treatment responses. The PDX Core will serve as a central resource for these specimens, linking clinical data and molecular genomics to better inform personalized cancer therapies. This initiative seeks to address health disparities in cancer treatment and outcomes.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals from racial and ethnic minority groups diagnosed with advanced cancer.
Not a fit: Patients who do not belong to underrepresented racial or ethnic groups or those with early-stage cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments for diverse populations.
How similar studies have performed: Previous research has shown success in using patient-derived models to improve cancer treatment, making this approach promising yet focused on underrepresented populations.
Where this research is happening
RICHMOND, UNITED STATES
- VIRGINIA COMMONWEALTH UNIVERSITY — RICHMOND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KOBLINSKI, JENNIFER E — VIRGINIA COMMONWEALTH UNIVERSITY
- Study coordinator: KOBLINSKI, JENNIFER E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Advanced Cancer, Breast Cancer