Creating blood vessel structures using air in 3D printing

3D Printing of Air: An Intangible Ink for Fabrication of Vascularized Tissues

NIH-funded research Pennsylvania State University, the · NIH-11135394

This study is exploring a new way to use air in 3D printing to create better tissues for organ transplants and healing, which could help patients get improved treatments without harmful leftovers from traditional methods.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPennsylvania State University, the NIH-funded
Lab location1 site (University Park, United States)
Project IDNIH-11135394 on NIH RePORTER

What this research studies

This research focuses on developing a novel 3D printing technology that uses air as an intangible ink to create vascularized tissues. By utilizing the compressibility of air within yield-stress gels, the project aims to generate stable open-channel networks in a single step, significantly improving the speed and efficiency of tissue fabrication. This approach addresses the current limitations of traditional sacrificial inks, which often leave harmful residues and require extensive post-processing. Patients may benefit from advancements in tissue engineering that could lead to better organ transplants and regenerative therapies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with conditions requiring tissue regeneration or organ transplants, particularly those affected by vascular diseases.

Not a fit: Patients with conditions that do not involve tissue or organ damage may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and faster methods for creating vascularized tissues, improving outcomes for patients needing organ transplants or tissue regeneration.

How similar studies have performed: While 3D bioprinting has shown promise in tissue engineering, the specific approach of using air as an ink is novel and has not been extensively tested in prior studies.

Where this research is happening

University Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Atherosclerotic Cardiovascular Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.