Creating bacterial sugars to understand infections
Chemoenzymatic synthesis of bacterial nonulosonic acids and glycans
This study is exploring how certain sugars made by bacteria help them survive and cause infections, with the goal of learning more about these sugars to improve our understanding of bacterial behavior and possibly create new vaccines.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-10755609 on NIH RePORTER |
What this research studies
This research focuses on developing methods to synthesize unique sugars produced by bacteria, which are important for their survival and ability to cause infections. By creating these bacterial sugars, researchers aim to study how they interact with the immune system and their role in bacterial infections. The project employs chemoenzymatic techniques, which combine chemical and enzymatic processes to produce these complex carbohydrates. Understanding these sugars could lead to new insights into bacterial behavior and potential vaccine development.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by bacterial infections or those at high risk for such infections.
Not a fit: Patients with viral infections or non-infectious diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccines and treatments for bacterial infections.
How similar studies have performed: Other research has shown promise in using similar approaches to develop vaccines and treatments targeting bacterial infections.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Chen, Xi — University of California at Davis
- Study coordinator: Chen, Xi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.