Creating and maintaining mouse models for brain tumors
Core 3: Mouse GBM models and Imaging Core
This study is creating a helpful resource for scientists working with mouse models of glioblastoma, a tough brain cancer, to make sure they can share reliable information and techniques, which could eventually lead to better treatments for patients like you.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10876421 on NIH RePORTER |
What this research studies
This research focuses on developing a centralized resource for mouse models of glioblastoma, a type of aggressive brain tumor. It aims to ensure consistency and reliability in the use of these models across various projects by providing access to a repository of mouse glioblastoma cells and expertise in their implantation and imaging. Patients may benefit indirectly through advancements in understanding and treating glioblastoma, as the findings could lead to improved therapies. The research involves engineering mouse cells to express specific genes and validating new tumor markers.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research are individuals diagnosed with glioblastoma or those at risk for developing this type of brain tumor.
Not a fit: Patients with other types of brain tumors or non-cancerous conditions may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for glioblastoma patients.
How similar studies have performed: Previous research has shown success in using mouse models to study glioblastoma, indicating that this approach is both established and promising.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Chiocca, E. Antonio — Brigham and Women's Hospital
- Study coordinator: Chiocca, E. Antonio
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.