Creating affordable sialoglycans for medical research and treatment
Affordable sialoglycans and associated reagents for expanded chemoenzymatic production
This study is working on a new, affordable way to make special sugars that can help with diseases like cancer and infections, so that patients can have better treatments and tests in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Integrated Micro-Chromatography Systems, INC. NIH-funded |
| Lab location | 1 site (Irmo, United States) |
| Project ID | NIH-10909153 on NIH RePORTER |
What this research studies
This research focuses on developing cost-effective methods to produce sialoglycans, which are important molecules involved in various biological processes and diseases, including cancer and infections. The team is utilizing a specialized technique called one-pot multienzyme (OPME) chemoenzymatic synthesis to create these complex sugars efficiently. By improving the production process, the research aims to make these valuable compounds more accessible for therapeutic and diagnostic applications. Patients may benefit from advancements in treatments that rely on these molecules.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals affected by cancers or bacterial infections who may require advanced diagnostic tools or treatments.
Not a fit: Patients with conditions unrelated to the biological roles of sialoglycans may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective diagnostics and therapies for conditions like cancer and bacterial infections.
How similar studies have performed: Previous research has shown promise in using chemoenzymatic methods for synthesizing complex carbohydrates, indicating a potential for success in this approach.
Where this research is happening
Irmo, United States
- Integrated Micro-Chromatography Systems, INC. — Irmo, United States (Active)
Researchers
- Principal investigator: Lee, Lim Andrew — Integrated Micro-Chromatography Systems, INC.
- Study coordinator: Lee, Lim Andrew
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.