Creating advanced 3D imaging techniques for studying cells and tissues
Official title: Building a Wide-field, High-resolution Histotomography Resource for Biology
Funded at Pennsylvania State Univ Hershey Med Ctr · NIH-11113841 · Data updated 2026-11-12
This study is working on a new 3D imaging technology that helps scientists look closely at cells and tissues in living organisms, which could lead to better understanding of how genes and the environment affect health and disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project start | June 15, 2024 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $934,127 |
| NIH project number | 5R24OD035407-02 |
| Project ID | NIH-11113841 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that affect tissue structure, such as cancer or genetic disorders.
✕Less likely to help
Patients with conditions that do not involve significant changes in tissue structure may not benefit from this research.
What this research studies
This research aims to develop a new 3D imaging technology called histotomography, which allows for detailed examination of cells and tissues in three dimensions. By using advanced X-ray tomography techniques, the project seeks to provide a comprehensive understanding of how genes and environmental factors influence the structure of tissues in living organisms. This innovative approach will enable researchers to analyze the entire anatomy of organisms, rather than just thin slices of tissue, leading to better insights into health and disease.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding diseases at a cellular level, improving diagnosis and treatment options for patients.
How similar studies have gone: Previous research using advanced imaging techniques has shown promise in enhancing our understanding of complex biological systems, indicating that this approach could also be successful.
Where this research is happening
-
Pennsylvania State Univ Hershey Med Ctr
Hershey, United States Active
Researchers
- Principal investigator: Cheng, Keith Chi — Pennsylvania State Univ Hershey Med Ctr
- Study coordinator: Cheng, Keith Chi
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.