NIH-funded research R01 grant

Creating a new wound dressing to speed up healing for diabetic patients

Official title: Engineering the open porous nanofibrous microsphere integrated fibrillar hydrogel for the co-delivery of antibacterial and angiogenic agents aimed at the rapid diabetic wound repair

Funded at Terasaki Institute for Biomedical Innovation · NIH-10873792 · Data updated 2026-11-12

This study is testing a new type of wound dressing made from tiny fibers and a gel that helps diabetic wounds heal faster by keeping them moist and delivering healing ingredients right where they're needed.

More Wound research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionTerasaki Institute for Biomedical Innovation
NIH-funded
Lab location1 site (Woodland Hills, UNITED STATES)
Project startJuly 1, 2023
Project endJune 30, 2028
Funding year2024
Award (this year)$476,801
NIH project number5R01DK134903-02
Project IDNIH-10873792 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with diabetic wounds that are slow to heal or at risk of infection.

Less likely to help

Patients with non-diabetic wounds or those who do not have chronic wound healing issues may not benefit from this research.

What this research studies

This research focuses on developing an innovative wound dressing made from special nanofibers and a gel that can release healing agents to help diabetic wounds heal faster. The dressing is designed to enhance cell movement and tissue formation, which are crucial for closing wounds effectively. By using advanced techniques to create a porous structure, the dressing aims to provide a moist environment and deliver antibacterial and angiogenic agents directly to the wound site. This approach could significantly improve the healing process for patients with diabetic wounds.

Why it matters

Potential benefit: If successful, this research could lead to faster and more effective healing of diabetic wounds, reducing the risk of complications such as infections and amputations.

How similar studies have gone: Previous research has shown promising results with similar approaches using nanofibrous scaffolds for wound healing, indicating potential for success in this novel application.

Where this research is happening

  • Terasaki Institute for Biomedical Innovation
    Woodland Hills, United States
    Active

Researchers

  • Principal investigator: Vitharikunnil John, Johnson — Terasaki Institute for Biomedical Innovation
  • Study coordinator: Vitharikunnil John, Johnson

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.