Creating a new vaccine adjuvant to improve Lyme disease vaccines
DEVELOPMENT OF COVALENTLY BOUND HYALURONIC ACID AS AN ADJUVANT FOR MULTIVALENT LYME DISEASE VACCINE
This study is testing a new way to make Lyme disease vaccines work better by using a special ingredient that helps boost the immune response, so people can have stronger protection against Lyme disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Design-Zyme, LLC NIH-funded |
| Lab location | 1 site (Lawrence, United States) |
| Project ID | NIH-11203936 on NIH RePORTER |
What this research studies
This research focuses on developing a new vaccine adjuvant made from covalently bound hyaluronic acid to enhance the effectiveness of Lyme disease vaccines. The approach involves using the OspC antigen from the Borrelia bacteria, which causes Lyme disease, to create a more robust immune response. By improving the vaccine's ability to stimulate the immune system, this research aims to provide better protection against Lyme disease. Patients may benefit from a more effective vaccine that could lead to fewer cases of Lyme disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk of Lyme disease, particularly those living in areas where Lyme disease is prevalent.
Not a fit: Patients who have already been vaccinated against Lyme disease or those who do not live in Lyme disease-endemic areas may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a more effective Lyme disease vaccine, reducing the incidence of the disease.
How similar studies have performed: Other research has shown promise in using adjuvants to enhance vaccine efficacy, suggesting that this approach could be beneficial.
Where this research is happening
Lawrence, United States
- Design-Zyme, LLC — Lawrence, United States (Active)
Researchers
- Principal investigator: Petillo, Peter a — Design-Zyme, LLC
- Study coordinator: Petillo, Peter a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.