Creating a new intervention for teens at risk of serious mental health issues

Development of a transdiagnostic intervention for adolescents at risk for serious mental illness

NIH-funded research Massachusetts General Hospital · NIH-10904937

This study is testing a group program called Resilience Training for teens aged 12 to 20 who show early signs of mental health challenges, aiming to help them understand social situations better and prevent more serious issues down the road.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10904937 on NIH RePORTER

What this research studies

This research focuses on developing an early intervention for adolescents aged 12 to 20 who exhibit subclinical psychotic symptoms, which can indicate a risk for serious mental illnesses. The approach involves a group-based program called Resilience Training, aimed at enhancing social cognition and functioning. By intervening during adolescence, a critical period for brain development, the research seeks to prevent the onset of more severe mental health issues. Participants will engage in activities designed to improve their understanding of social cues and mental states, potentially leading to better mental health outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who are showing early signs of psychotic symptoms or significant psychiatric distress.

Not a fit: Patients who are already diagnosed with serious mental illnesses may not benefit from this early intervention approach.

Why it matters

Potential benefit: If successful, this research could significantly reduce the risk of developing serious mental illnesses in adolescents.

How similar studies have performed: Previous trials of the Resilience Training program have shown promising results in reducing symptoms and improving social functioning, indicating a potential for success in this new application.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Affective DisordersAnxiety Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.