Creating a new intervention for teens at risk of serious mental health issues
Official title: Development of a transdiagnostic intervention for adolescents at risk for serious mental illness
Funded at Massachusetts General Hospital · NIH-10904937 · Data updated 2026-11-12
This study is testing a group program called Resilience Training for teens aged 12 to 20 who show early signs of mental health challenges, aiming to help them understand social situations better and prevent more serious issues down the road.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 10, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $161,589 |
| NIH project number | 5K23MH131793-02 |
| Project ID | NIH-10904937 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 12 to 20 who are showing early signs of psychotic symptoms or significant psychiatric distress.
✕Less likely to help
Patients who are already diagnosed with serious mental illnesses may not benefit from this early intervention approach.
What this research studies
This research focuses on developing an early intervention for adolescents aged 12 to 20 who exhibit subclinical psychotic symptoms, which can indicate a risk for serious mental illnesses. The approach involves a group-based program called Resilience Training, aimed at enhancing social cognition and functioning. By intervening during adolescence, a critical period for brain development, the research seeks to prevent the onset of more severe mental health issues. Participants will engage in activities designed to improve their understanding of social cues and mental states, potentially leading to better mental health outcomes.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of developing serious mental illnesses in adolescents.
How similar studies have gone: Previous trials of the Resilience Training program have shown promising results in reducing symptoms and improving social functioning, indicating a potential for success in this new application.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Detore, Nicole R. — Massachusetts General Hospital
- Study coordinator: Detore, Nicole R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.