Creating a digital model of the liver to improve cancer treatment
Official title: A liver digital twin for personalized cancer therapy
Funded at University of California at Davis · NIH-10992569 · Data updated 2026-11-12
This study is working on a new way to make liver cancer treatments safer and more effective by using computer technology to create a digital model of your liver, helping doctors personalize the best treatment plan for you during a procedure called transarterial embolization.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | September 17, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $357,939 |
| NIH project number | 1U01CA289068-01A1 |
| Project ID | NIH-10992569 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with advanced liver cancer who are considering or undergoing transarterial embolization treatments.
✕Less likely to help
Patients with early-stage liver cancer or those not eligible for transarterial embolization may not benefit from this research.
What this research studies
This research aims to enhance the effectiveness and safety of liver cancer treatments by developing advanced computational tools that create a digital twin of the liver. By utilizing artificial intelligence, the project seeks to personalize treatment strategies for patients undergoing transarterial embolization, a procedure that blocks blood flow to tumors while delivering targeted therapies. The study will analyze patient-specific data to optimize treatment plans, potentially leading to better outcomes and reduced side effects. The research addresses the challenges of current imaging techniques that often result in inadequate dosing and incomplete tumor treatment.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer therapies, improving survival rates and quality of life for liver cancer patients.
How similar studies have gone: Previous research has shown promising results with personalized treatment approaches in cancer therapy, indicating potential for success in this novel application.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Roncali, Emilie — University of California at Davis
- Study coordinator: Roncali, Emilie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.