Creating a 3D device to study kidney and cardiovascular disease mechanisms
Official title: Engineered 3D microfluidic tubular device as multimodal, functional tissue model
Funded at U.s. Dept/vets Affairs Medical Center · NIH-10920891 · Data updated 2026-11-12
This study is creating a special 3D device that simulates how kidneys and heart tissues work to learn more about how harmful calcium deposits form, which could help develop better treatments for related health problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | U.s. Dept/vets Affairs Medical Center NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project start | July 1, 2024 |
| Project end | September 30, 2027 |
| Funding year | 2024 |
| NIH project number | 1I21BX006418-01A1 |
| Project ID | NIH-10920891 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from kidney or cardiovascular diseases, particularly those with conditions related to calcium phosphate deposits.
✕Less likely to help
Patients with unrelated health conditions or those not affected by kidney or cardiovascular diseases may not benefit from this research.
What this research studies
This research focuses on developing a novel 3D microfluidic device that mimics the natural environment of kidney and cardiovascular tissues. By recreating these conditions, the researchers aim to better understand how calcium phosphate deposits form, which are linked to serious health issues. The approach involves using advanced technology to control the biological conditions in real-time, allowing for a more accurate study of the processes involved in mineralization and stone formation. Patients may benefit from insights gained that could lead to new therapies for related diseases.
Why it matters
Potential benefit: If successful, this research could lead to new clinical therapies for kidney and cardiovascular diseases associated with calcium phosphate deposits.
How similar studies have gone: While there has been extensive research on calcium phosphate deposits, this approach using a 3D microfluidic system is relatively novel and has not been widely tested.
Where this research is happening
-
U.s. Dept/vets Affairs Medical Center
Washington, United States Active
Researchers
- Principal investigator: Bandyopadhyay, Bidhan Chandra — U.s. Dept/vets Affairs Medical Center
- Study coordinator: Bandyopadhyay, Bidhan Chandra
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.