Cooled Radiofrequency Bronchoscopic Lung Volume Reduction for Emphysema
Official title: Cooled RF Bronchoscopic Lung Volume Reduction
Funded at Coridea, LLC · NIH-11349295 · Data updated 2026-11-12
A new, minimally invasive therapy uses cooled radiofrequency to reduce lung volume in adults with advanced emphysema-related COPD.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Coridea, LLC NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 1, 2026 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $305,365 |
| NIH project number | 1R43HL186091-01 |
| Project ID | NIH-11349295 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with severe emphysema who have limited options for current lung-volume-reduction treatments.
✕Less likely to help
Patients without severe emphysema or those who are not candidates for bronchoscopic procedures may not benefit.
What this research studies
This project targets adults with severe emphysema, a form of COPD, who struggle to breathe due to damaged lung tissue. Using a bronchoscope, a cooled radiofrequency device will be applied to shrink overexpanded areas of the lung to improve airflow. The goal is to provide a less invasive alternative to surgery or valve implants, with potential for quicker recovery and broader eligibility. The study will assess safety and early effectiveness in patients who currently have few good treatment options.
Why it matters
Potential benefit: If successful, this approach could improve breathing and quality of life for people with severe emphysema who cannot undergo valve therapy or surgery.
How similar studies have gone: Earlier lung-volume reduction methods showed promise, but this specific cooled RF approach is exploratory and its effectiveness is not yet proven.
Where this research is happening
-
Coridea, LLC
New York, United States Active
Researchers
- Principal investigator: Levin, Howard — Coridea, LLC
- Study coordinator: Levin, Howard
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.