CONNECT: Multilevel support to help women stick with endocrine breast cancer therapy
Official title: CONNECT: Combining Navigation, Networks, and Electronic monitoring to improve endoCrine Therapy adherence
Funded at Thomas Jefferson University · NIH-11433676 · Data updated 2026-11-12
A study at Thomas Jefferson University aims to help women with hormone receptor–positive breast cancer stay on endocrine therapy longer by combining navigation, social connections, and smart monitoring.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Thomas Jefferson University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | August 12, 2026 |
| Project end | July 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $651,545 |
| NIH project number | 1R01CA318624-01 |
| Project ID | NIH-11433676 on NIH RePORTER |
Who could benefit from this research
✓Could help
Women with hormone receptor–positive breast cancer who are prescribed 5–10 years of endocrine therapy.
✕Less likely to help
Patients not on endocrine therapy or without access to the involved care team and monitoring tools may not benefit.
What this research studies
This project builds on prior work showing that adding smart pill bottles to standard care improves adherence but isn’t enough to sustain it long-term. It introduces CONNECT, a multilevel program that adds navigation and social networks to electronic monitoring to support patients through 5–10 years of endocrine treatment. The approach focuses on real-world use, patient experiences, and changes in daily life, with ongoing monitoring to adapt support as needs evolve. If successful, it could help more patients maintain therapy, reduce recurrence risk, and improve quality of life.
Why it matters
Potential benefit: If successful, patients could experience higher adherence to endocrine therapy, potentially lowering cancer recurrence and improving long-term quality of life.
How similar studies have gone: Earlier studies showed improved adherence with enhanced monitoring, but long-term sustainability required multilevel support.
Where this research is happening
-
Thomas Jefferson University
Philadelphia, United States Active
Researchers
- Principal investigator: Badr, Hoda J. — Thomas Jefferson University
- Study coordinator: Badr, Hoda J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.