Comparing two medications for managing low blood pressure during major surgeries.
PHEnylephrine versus NOrepinephrine in Major NONcardiac surgery (PHENOMeNON): Foundational Studies for a Pragmatic Randomized Clinical Trial.
This study is looking at how two medications, norepinephrine and phenylephrine, help treat low blood pressure during major surgeries, and it aims to find out which one works better for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11021098 on NIH RePORTER |
What this research studies
This research investigates how two different medications, norepinephrine and phenylephrine, are used to treat low blood pressure that can occur during major surgeries requiring general anesthesia. It aims to gather data on current practices and clinician opinions regarding these medications across various institutions. The findings will help develop a pilot clinical trial to determine which medication is more effective in improving patient outcomes during surgery. Patients undergoing major non-cardiac surgeries may be directly impacted by the results of this research.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are scheduled for major non-cardiac surgeries requiring general anesthesia.
Not a fit: Patients who are not undergoing major surgeries or those who do not require general anesthesia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved management of low blood pressure during surgeries, potentially reducing complications like kidney injury and enhancing overall patient safety.
How similar studies have performed: Previous research has shown varying success in the use of vasopressors during surgery, indicating that this area is still actively being explored and holds potential for new insights.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Janda, Allison Mary — University of Michigan at Ann Arbor
- Study coordinator: Janda, Allison Mary
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.