Comparing treatments for opioid use disorder in pregnant women
The Comparative Effectiveness and Safety of Pharmacotherapies for the Treatment of Opioid Use Disorder in Pregnancy
This study is looking at how well different medications for opioid use disorder work and how safe they are for pregnant women and their babies, with the goal of finding better ways to support moms-to-be who are dealing with this issue.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11194370 on NIH RePORTER |
What this research studies
This research investigates the effectiveness and safety of different medications used to treat opioid use disorder (OUD) in pregnant women. It aims to understand how treatments like buprenorphine and methadone impact both maternal and fetal health, particularly in relation to risks such as neonatal abstinence syndrome and preterm delivery. The study also examines the challenges of maintaining treatment during and after pregnancy, especially in the presence of other substance use disorders. By analyzing these factors, the research seeks to improve treatment strategies for pregnant patients with OUD.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women diagnosed with opioid use disorder who are receiving or considering medication-assisted treatment.
Not a fit: Patients who are not pregnant or those without a diagnosis of opioid use disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment protocols that enhance the health outcomes for both mothers and their babies.
How similar studies have performed: Previous research has shown promising results in comparing different medications for opioid use disorder, indicating that this approach has potential for significant findings.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Huybrechts, Krista F — Brigham and Women's Hospital
- Study coordinator: Huybrechts, Krista F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.