NIH-funded research R01 grant

Comparing how different ACL surgeries affect muscle function

Official title: Neuromuscular response to competing ACL surgeries

Funded at Rhode Island Hospital · NIH-10995417 · Data updated 2026-11-12

This study is looking at how two different surgeries for ACL injuries—one that keeps more of your knee's natural parts (called BEAR) and the standard surgery (ACLR)—affect how well your muscles recover and how your knee moves, to see if one method helps you heal better than the other.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRhode Island Hospital
NIH-funded
Lab location1 site (Providence, United States)
Project startJuly 30, 2024
Project endJune 30, 2028
Funding year2024
Award (this year)$400,526
NIH project number1R01AR083168-01A1
Project IDNIH-10995417 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who have suffered an ACL injury and are considering surgical intervention.

Less likely to help

Patients who have already undergone ACL surgery or those with non-ACL related knee injuries may not benefit from this research.

What this research studies

This research investigates the differences in muscle recovery and joint motion between two surgical approaches for anterior cruciate ligament (ACL) injuries: the novel bridge-enhanced ACL restoration (BEAR) and the standard ACL reconstruction (ACLR). By analyzing patients from the BEAR-MOON Trial, the study aims to understand how these surgeries impact neuromuscular function and overall recovery. The researchers will evaluate muscle strength and joint motion over time to determine if the BEAR method, which preserves more of the knee's natural structures, leads to better outcomes than ACLR. This could provide valuable insights into optimizing surgical techniques for ACL injuries.

Why it matters

Potential benefit: If successful, this research could lead to improved surgical techniques that enhance recovery and reduce the risk of long-term complications for patients with ACL injuries.

How similar studies have gone: Other research has shown promising results in preserving neuromuscular function with innovative surgical techniques, suggesting potential for success in this approach.

Where this research is happening

  • Rhode Island Hospital
    Providence, United States
    Active

Researchers

  • Principal investigator: Beveridge, Jillian Elizabeth — Rhode Island Hospital
  • Study coordinator: Beveridge, Jillian Elizabeth

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.