Comparing a new device for ACL repair with standard surgery
BEAR-MOON: A Two Arm Noninferiority Blinded Randomized Clinical Trial Comparing ACL Repair with BEAR Device vs. Standard of Care Autograft Patellar Tendon ACL Reconstruction
This study is looking at a new device called the BEAR to see if it works better than the usual surgery for fixing ACL injuries, and it's for people who have had this type of knee injury and want to know which treatment might help them heal and stay active longer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10686051 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of a new device called the BEAR (Bridge-Enhanced ACL Repair) in repairing anterior cruciate ligament (ACL) injuries compared to the traditional method of using a graft from the patient's own body. The study involves a randomized clinical trial where participants will be assigned to receive either the BEAR device or standard ACL reconstruction surgery. The goal is to evaluate the healing outcomes and knee stability after treatment, with a focus on preventing early post-traumatic osteoarthritis. Patients will be monitored for their recovery and overall knee function over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have sustained an ACL injury and are considering surgical repair options.
Not a fit: Patients with chronic ACL injuries or those who have previously undergone ACL reconstruction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a less invasive and more effective treatment for ACL injuries, reducing the risk of long-term complications.
How similar studies have performed: Previous studies on the BEAR device have shown promising results, indicating that this approach could be a significant advancement in ACL repair techniques.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Spindler, Kurt Paul — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Spindler, Kurt Paul
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.