Combining complex brain data and tissue samples for better diagnosis and treatment
Official title: Integration and interoperability of complex data and tissues from the human brain
Funded at University of Illinois at Chicago · NIH-10932428 · Data updated 2026-11-12
This study is looking at different types of health information about the brain to help doctors better diagnose and treat brain disorders, and if you're having brain surgery for seizures, you can help by sharing your tissue samples and health data.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project start | September 20, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $1,032,521 |
| NIH project number | 5UG3TR004501-02 |
| Project ID | NIH-10932428 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are individuals aged 21 and older who are undergoing complex brain surgeries for conditions such as seizures.
✕Less likely to help
Patients with brain disorders who are not undergoing surgical interventions or are younger than 21 may not benefit from this research.
What this research studies
This research focuses on integrating various types of health data related to the human brain, including electronic health records, imaging, and genomic studies, to improve diagnosis and treatment plans. It utilizes a unique brain tissue bank where each sample is linked to a comprehensive dataset, allowing for a more holistic understanding of brain disorders. The project employs a specialized software platform called INTUITION to analyze and interpret this complex data, aiming to uncover new biomarkers and therapeutic targets. Patients undergoing brain surgeries for seizures may contribute to this research, which seeks to enhance clinical care and advance brain research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and personalized treatment plans for patients with brain disorders.
How similar studies have gone: Previous studies using similar approaches have shown success in identifying important biomarkers and therapeutic targets in brain research.
Where this research is happening
-
University of Illinois at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Loeb, Jeffrey a — University of Illinois at Chicago
- Study coordinator: Loeb, Jeffrey a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.