NIH-funded research R01 grant

Cohort study following older adults to understand aging, memory loss, and dementia over time

Official title: The Northern Ireland Cohort for the Longitudinal Study of Aging

Funded at Queen's University Belfast · NIH-11366098 · Data updated 2026-11-12

A long-term study of people aged 65 and older to learn more about aging, memory problems, dementia, and related health factors.

More Aging research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionQueen's University Belfast
NIH-funded
Lab location1 site (Belfast, United Kingdom)
Project startSeptember 1, 2026
Project endAugust 31, 2031
Funding year2026
Award (this year)$1,092,659
NIH project number1R01AG091464-01A1
Project IDNIH-11366098 on NIH RePORTER

Who could benefit from this research

Could help

Adults aged 65 and older who participate in NICOLA or similar aging cohorts and are willing to provide data over multiple years.

Less likely to help

Participants not interested in long-term follow-up or cognitive assessments may not directly benefit.

What this research studies

This project continues the NICOLA cohort to collect another round of data on aging, cognition, health conditions, and biomarkers in older adults. It includes detailed cognitive testing with the Harmonized Cognitive Assessment Protocol and plans for data linkage to help researchers study aging patterns relevant to the US population. The research team will explore how social, environmental, and biological factors influence frailty, memory loss, and care needs over time. The findings could inform strategies to prevent or manage dementia and improve quality of life for older adults.

Why it matters

Potential benefit: It could lead to better understanding of aging and dementia, informing prevention, care planning, and health policies for older adults.

How similar studies have gone: Longitudinal aging cohorts have shown valuable insights into cognitive aging and dementia risk, with growing data resources.

Where this research is happening

  • Queen's University Belfast
    Belfast, United Kingdom
    Active

Researchers

  • Principal investigator: Mcguinness, Bernadette — Queen's University Belfast
  • Study coordinator: Mcguinness, Bernadette

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.