Cleveland COPE-AKI Clinical Center: Better Care After Acute Kidney Injury
Official title: Cleveland COPE-AKI Clinical Center
Funded at Cleveland Clinic Lerner Com-Cwru · NIH-11518280 · Data updated 2026-11-12
A new program helps people who survived a hospital-based acute kidney injury receive more coordinated follow-up care to prevent kidney and health problems later.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | July 19, 2021 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $804,116 |
| NIH project number | 5U01DK129980-06 |
| Project ID | NIH-11518280 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults who have survived an AKI event (stage 2 or 3) and are at risk for long-term kidney problems.
✕Less likely to help
Patients without a recent AKI or those not transitioning to outpatient care may not benefit.
What this research studies
This project creates a dedicated care pathway for AKI survivors after hospital discharge, using a nephrologist-guided team and a nurse navigator to monitor blood pressure and protein in the urine. Care is delivered through a structured, remote/virtual approach aligned with KDIGO guidelines, aiming to reduce major kidney-related problems over two years. Patients will receive regular monitoring, education, and coordinated follow-up to address kidney function, blood pressure, and volume status. The goal is to improve quality of life, lower costs, and prevent progression to chronic kidney disease or end-stage kidney disease.
Why it matters
Potential benefit: If successful, this program could reduce kidney damage, improve wellbeing, and lower healthcare costs for AKI survivors.
How similar studies have gone: Previous care-management approaches have shown promise in reducing adverse kidney outcomes, but this trial tests a comprehensive Champion Care Pathway.
Where this research is happening
-
Cleveland Clinic Lerner Com-Cwru
Cleveland, United States Active
Researchers
- Principal investigator: Poggio, Emilio Daniel — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Poggio, Emilio Daniel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.