Children’s Oncology Group Clinical Trials leadership and oversight
Official title: Development, review, and conduct of Children's Oncology Group (COG) Clinical Trials
Funded at Children's Research Institute · NIH-11383122 · Data updated 2026-11-12
A national network is coordinating and guiding pediatric cancer clinical trials to improve treatment, care, and survival for children and teens with cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Research Institute NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project start | September 20, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $142,360 |
| NIH project number | 5R50CA275931-04 |
| Project ID | NIH-11383122 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children and adolescents up to about 21 years old who are treated at COG member institutions and may participate in COG trials.
✕Less likely to help
Not all patients will benefit directly, as trial outcomes depend on disease type, stage, and response to therapy.
What this research studies
This grant supports the organization and oversight of pediatric cancer clinical trials through the Children’s Oncology Group, which includes centers across the United States. It focuses on refining frontline therapies, exploring new approaches for recurrent disease, understanding cancer biology, and improving survivorship and quality of life. The work involves central protocol development and local trial conduct at over 200 sites, under experienced leadership. If you or your child were enrolled in a COG trial, this kind of oversight helps ensure trials are well-designed and safely run.
Why it matters
Potential benefit: If successful, this program could lead to safer, more effective treatments and better long-term outcomes for children with cancer.
How similar studies have gone: COG has a long track record with thousands of patients enrolled and multiple trials advancing frontline therapy and supportive care.
Where this research is happening
-
Children's Research Institute
Washington, United States Active
Researchers
- Principal investigator: Dome, Jeffrey S — Children's Research Institute
- Study coordinator: Dome, Jeffrey S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.