Central tissue hub for lupus, rheumatoid arthritis, Sjögren’s, and psoriatic disease
Official title: Accelerating Medicines Partnership-Autoimmune and Immunologic Disease Tissue Research Core
Funded at Oklahoma Medical Research Foundation · NIH-11307653 · Data updated 2026-11-12
This project collects and shares high-quality tissue and blood samples from people with lupus, rheumatoid arthritis, Sjögren’s, and psoriatic disease so researchers can develop better tests and treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oklahoma Medical Research Foundation NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project start | March 23, 2022 |
| Project end | December 31, 2026 |
| Funding year | 2026 |
| Award (this year) | $7,449,999 |
| NIH project number | 5UC2AR081032-05 |
| Project ID | NIH-11307653 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are people diagnosed with lupus (SLE), rheumatoid arthritis, Sjögren’s disease, or psoriatic-spectrum disorders who can provide blood and/or tissue samples and share clinical information.
✕Less likely to help
People without these specific autoimmune diagnoses or those unwilling or unable to provide tissue or blood samples (including biopsies) are unlikely to benefit from participating.
What this research studies
If I take part, the team will collect blood and target tissue samples using standardized methods and share them with a central lab. My samples will get quality checks, imaging, and advanced single-cell and spatial analyses to map cell types and molecules. The core organizes sample transport, storage, and testing for multiple autoimmune disease teams so results are comparable across sites. This centralized approach helps researchers compare disease tissues and look for common or distinct biological signals.
Why it matters
Potential benefit: If successful, this work could speed creation of new biomarkers and targeted therapies that improve diagnosis and care for people with these autoimmune diseases.
How similar studies have gone: Earlier AMP work in rheumatoid arthritis and lupus used single-cell methods to produce useful tissue maps and biological leads, and this project expands that proven approach to more diseases and spatial technologies.
Where this research is happening
-
Oklahoma Medical Research Foundation
Oklahoma City, United States Active
Researchers
- Principal investigator: Guthridge, Joel Marvin — Oklahoma Medical Research Foundation
- Study coordinator: Guthridge, Joel Marvin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.