Central hub coordinating work on IgG4-related autoimmune disease
Administrative Core
This program brings together researchers, clinicians, and lab tools to better understand IgG4-related autoimmune disease and connect patients with sample collection and collaboration opportunities.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11323976 on NIH RePORTER |
What this research studies
Researchers and coordinators meet monthly at Massachusetts General Hospital (with virtual options) to plan studies and arrange sample collection related to IgG4-related disease. The Core provides laboratory services such as next-generation immune repertoire sequencing, detailed immune cell and tissue profiling, and secure sample storage to support multiple projects. The coordinator also links MGH clinicians and investigators who want to work together or refer patients for related studies. A shared data portal will let this team exchange immune, microbial community, and chromatin information with other centers to speed discoveries.
Who could benefit from this research
Good fit: People diagnosed with IgG4-related disease (or patients at MGH being evaluated for suspected IgG4-related disease) who are willing to provide clinical information or biological samples are the best fit.
Not a fit: Patients without IgG4-related disease, those unwilling to travel to Boston or provide samples, or those seeking an immediate treatment are unlikely to benefit directly from this Core.
Why it matters
Potential benefit: If successful, this coordination and shared infrastructure could speed discovery of causes and diagnostics and help design better treatments for people with IgG4-related disease.
How similar studies have performed: Other research cores using shared coordination, sequencing, and profiling have helped advance understanding of autoimmune conditions, though IgG4-related disease still needs more study.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Pillai, Shiv Subramaniam — Massachusetts General Hospital
- Study coordinator: Pillai, Shiv Subramaniam
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.