Center for how substance use raises chronic disease risk
Center for Addiction and Disease Risk Exacerbation
This center follows people who use alcohol, nicotine, or cannabis and people with chronic illnesses to learn how substance use, sleep, and mood change disease risk and outcomes over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brown University NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project ID | NIH-11179287 on NIH RePORTER |
What this research studies
The center funds multiple linked projects and early-career researchers who run long-term, prospective studies that follow people over months and years. Teams collect clinical measures, surveys about mood and sleep, and substance-use information, and they may use biological samples or lab tests to link behavior with disease changes. Specific projects include looking at alternative nicotine products and obesity-related outcomes and how sleep and negative mood connect cannabis use to depression. The goal is to find patterns that could point to better prevention or treatment approaches.
Who could benefit from this research
Good fit: People who use alcohol, tobacco (including vaping or other nicotine products), or cannabis and who have—or are at risk for—chronic conditions such as obesity or mood disorders are most likely to be eligible.
Not a fit: People without any history of substance use or any chronic health condition, or those needing immediate clinical care rather than research participation, are unlikely to benefit directly from this grant.
Why it matters
Potential benefit: If successful, this work could point to new ways to prevent and treat chronic diseases in people who use substances by targeting sleep, mood, or specific tobacco products.
How similar studies have performed: Prior studies have linked substance use to worse chronic disease outcomes, but this center's coordinated, longitudinal approach is broader and aims to fill gaps in how sleep and mood drive those links.
Where this research is happening
Providence, United States
- Brown University — Providence, United States (Active)
Researchers
- Principal investigator: Monti, Peter M. — Brown University
- Study coordinator: Monti, Peter M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.