NIH-funded research R21 grant

CASE: A practical sports test to guide kids back after concussion

Official title: A Clinical Assessment of Sports and Physical Exertion (CASE) in Children with Concussion

Funded at Spaulding Rehabilitation Hospital · NIH-11351723 · Data updated 2026-11-12

A child-focused test called CASE will check how a child recovers after a concussion so doctors can decide when it’s safe to return to sports.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionSpaulding Rehabilitation Hospital
NIH-funded
Lab location1 site (Charlestown, United States)
Project startJuly 1, 2026
Project endJune 30, 2028
Funding year2026
Award (this year)$480,192
NIH project number1R21HD121921-01
Project IDNIH-11351723 on NIH RePORTER

Who could benefit from this research

Could help

Children with concussion, ages 5–18, who are undergoing return-to-play assessment.

Less likely to help

Children without concussion or those not in the stages of RTP assessment may not benefit from this tool.

What this research studies

This grant supports developing and testing a practical, low-cost exercise-based tool to measure a child’s readiness to return to play after concussion. It uses a multimodal approach, includes dynamic movement, and relies on affordable equipment so it can be used in schools and clinics. The goal is to provide clear, objective information that complements the traditional symptom-based steps in the return-to-play protocol. By identifying ongoing physiological recovery needs, this work aims to reduce the risk of re-injury and shorten recovery times for children. The study will be conducted at a major rehabilitation hospital and involves a pediatric population with concussion.

Why it matters

Potential benefit: If successful, this tool could help clinicians make safer return-to-play decisions for children after concussion.

How similar studies have gone: Previous tools have addressed symptom reporting but lacked a comprehensive, dynamic, low-cost approach; this study builds on existing concepts with broader domain coverage.

Where this research is happening

  • Spaulding Rehabilitation Hospital
    Charlestown, United States
    Active

Researchers

  • Principal investigator: O'neil, Morgan a — Spaulding Rehabilitation Hospital
  • Study coordinator: O'neil, Morgan a

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.